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Bicalutamide
Item number: TGM-T0380-100mg
Description: Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. Target: Androgen Receptor, Autophagy. Smiles: CC(O)(CS(=O)(=O)C1=CC=C(F)C=C1)C(=O)NC1=CC(=C(C=C1)C#N)C(F)(F)F....
| Keywords: | ICI-176334 |
| CAS | 90357-06-5 |
| MW: | 430.37 D |
From 33.00€
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Bicalutamide
Item number: Cay14250-50
Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 µM, IC50 = 1.2 µM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation...
| Keywords: | ICI 176334, ZD 176334, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-propanamide |
| Application: | Androgen receptor antagonist, Metabolic studies |
| CAS | 90357-06-5 |
| MW: | 430.4 D |
From 43.00€
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Bicalutamide
Item number: LKT-B3209.1
A nonsteroidal antiandrogen, which has been shown effective in the treatment of prostate cancer. It has also been shown to induce cell death by a pathway that is independent of changes in mitochondrial membrane potential and Bcl-2 actions.
| Keywords: | Casodex, Cosudex, Calutide, Kalumid |
| Application: | Apoptosis inducer |
| CAS | 90357-06-5 |
| MW: | 430,37 D |
From 108.00€
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