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AT7519 Hydrochloride
Item number: TGM-T1778-10mg
Description: AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9. Target: Apoptosis, CDK, GSK-3. Smiles: Cl.Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1. References: Squires MS, et al. Mol Cancer Ther, 2009, 8(2), 324-332.
| Keywords: | AT7519 HCl, AT 7519 hydrochloride salt |
| Application: | CDK inhibitor |
| CAS | 902135-91-5 |
| MW: | 418.71 D |
From 52.00€
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AT7519 (hydrochloride)
Item number: Cay16231-1
AT7519 is an ATP-competitive inhibitor of cyclin-dependent kinases (Cdks) with IC50 values of 210, 47, 100, 13, 170, and 50 = 89 nM). AT7519 demonstrates antiproliferative activity against a wide variety of human tumor cell lines (IC50s = 40-940 nM in vitro), inhibiting cell cycle progression and inducing apoptosis,...
| Keywords: | 4-[(2,6-dichlorobenzoyl)amino]-N-4-piperidinyl-1H-pyrazole-3-carboxamide, monohydrochloride |
| Application: | CDK inhibitor |
| CAS | 902135-91-5 |
| MW: | 418.7 D |
From 43.00€
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AT7519 hydrochloride
Item number: SYN-1010-M001
Soluble in DMSO or ethanol. AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519...
| Keywords: | AT-7519 |
| Application: | CDK2 / CDK7 / CDK5 / CDK4 inhibitor |
| CAS | 902135-91-5 |
| MW: | 418,7 D |
From 79.00€
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AT-7519 Hydrochloride
Item number: LKT-A761003.100
| Keywords: | AT 7519 HCl, 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide hydrochloride,... |
| Application: | CDK inhibitor |
| CAS | 902135-91-5 |
| MW: | 418.7 D |
From 132.00€
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