Description: Dextran sulfate sodium salt (MW 4500-5500) is an anhydrous glucose polymer with a molecular weight range of 4500-5500. It inhibits human immunodeficiency virus replication by preventing viral adsorption to host cells and is commonly used to model inflammatory bowel disease. The high negative charge from...

Useful in nucleic acid hybridization. Source: Leuconoctoc Mesenteroides. CAS No: 9011-18-1, Molecular Weight: ~500kD, Appearance: Off-white to light yellow powder, Specific Rotation: +75º to +105º, pH (1%): 5.0-7.5, Loss on Drying: <10%, Residue on Ignition: 40-50%, Solubility: H2O, 100mg/mL, Chloride: <0.1%,...

Dextran sulfate is a sulfated polysaccharide of variable molecular weight ranging from 5 to 1,400 kDa. Oral administration of dextran sulfate induces colonic inflammation in a mouse model of inflammatory bowel disease (IBD). Acute, chronic, and relapsing models of IBD can be induced by varying the concentration and...

Dextran Sulfate (MW > 500,000) is used as an additive in probe hybridization solutions. Its presence accelerates the rate of hybridization by 10 fold. The addition of Dextran Sulfate favors the formation of probe networks, resulting in greater sensitivity during membrane-bound nucleic acid analysis. The product is...