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Item number: TGM-T3439-100mg

Description: ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM. Target: Phospholipase, Others. Smiles: FC(F)(F)c1ccc(Cl)c(NC(=O)CN2CCN(CC2)C(=O)c2ccco2)c1. References: Adibekian A, et al. National Center for Biotechnology Information (US), 2010-.2013 Apr...

Keywords:	GNF-Pf-1127
Application:	Reversible LYPLA1 inhibitor
CAS	899713-86-1
MW:	415.79 D

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ML-348

Item number: Cay18523-1

Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-348 is a reversible LYPLA1...

Keywords:	CID 3238952, SID 160654487, N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide
Application:	Reversible LYPLA1 inhibitor
CAS	899713-86-1
MW:	415.8 D

From 44.00€ *

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