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Item number: TGM-T5178-100mg

Description: AZ876 is a potent, highly selective LXR agonist with Ki/EC50 of 7/6 nM and 11/73 nM for hLXRalpha and hLXRbeta respectively. Target: Liver X Receptor. Smiles: CC(C)(C)N1C(=O)C(Nc2ccc(cc2)N2CCCCC2)=C(c2ccccc2)S1(=O)=O. References: van der Hoorn J et al. Low dose of the liver X receptor agonist, AZ876,...

Application:	LXR agonist
CAS	898800-26-5
MW:	439.57 D

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AZ876

Item number: Cay34413-5

AZ876 is a liver X receptor (LXR) agonist. It activates LXRalpha and LXRbeta in a transactivation assay in U2OS osteosarcoma cells (EC50 = 6 and 73 nM, respectively). AZ876 reduces phenylephrine-induced increases in cell size and protein synthesis in isolated neonatal rat ventricular myocytes. It decreases plasma...

Keywords:	2-(1,1-dimethylethyl)-5-phenyl-4-[[4-(1-piperidinyl)phenyl]amino]-3(2H)-isothiazolone, 1,1-dioxide
Application:	LXR agonist
CAS	898800-26-5
MW:	439.6 D

From 65.00€ *

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