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Item number: TGM-T3176-100mg

Description: APD597 (JNJ-38431055) is a GPR119 agonist, used in the treatment of type 2 diabetes. Target: GPR. Smiles: COc1c(Nc2ccc(nc2C)S(C)(=O)=O)ncnc1OC1CCN(CC1)C(=O)OC(C)C. References: Buzard DJ, et al. Bioorg Med Chem Lett. 2014 Sep 1,24(17):4332-5.

Keywords:	JNJ-38431055
Application:	GPR119 agonist
CAS	897732-93-3
MW:	479.55 D

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APD597

Item number: Cay22950-10

APD597 is an orally bioavailable agonist of GPR119 that has EC50 values of 46 and 421 nM for the human and rat receptors, respectively, in a homologous time-resolved fluorescence (HTRF) assay. It increases insulin secretion stimulated by a high, but not low, concentration of glucose in isolated mouse pancreatic...

Keywords:	JNJ-38431055, 4-[[5-methoxy-6-[[2-methyl-6-(methylsulfonyl)-3-pyridinyl]amino]-4-pyrimidinyl]oxy]-1-piperidinecarboxylic...
Application:	GPR119 agonist
CAS	897732-93-3
MW:	479.6 D

From 128.00€ *

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