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Item number: TGM-T3992-100mg

Description: MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM). Target: CXCR. Smiles: C(Nc1ncccn1)c1ccc(CNc2ncccn2)cc1. References: Liang Z, et al. Development of a unique small molecule modulator of CXCR4. PLoS One. 2012,7(4):e34038.

Keywords:	MSX122, MSX 122
Application:	CXCR4 partial antagonist
CAS	897657-95-3
MW:	292.34 D

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MSX-122

Item number: Cay23426-1

MSX-122 is a small molecule partial antagonist of C-X-C chemokine 4 (CXCR4, IC50 = ~10 nM). It reduces inflammation and infiltration of CXCR4+ cells in a dextran sulfate (Cay-23250) model of experimental colitis in mice. Specifically, it prevents the production of TNF-alpha, IL-1beta, and IL-6. MSX-122 also reduces...

Keywords:	N1,N4-di-2-pyrimidinyl-1,4-benzenedimethanamine
Application:	CXCR4 partial antagonist
CAS	897657-95-3
MW:	292.3 D

From 50.00€ *

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