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Tirbanibulin
Item number: TGM-T6345-100mg
Description: Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of colon, pancreatic, prostate and breast cancer. It is a substrate-targeted kinase inhibitor. KX2-391, belongs to an emerging new family of targeted cancer treatments called...
| Keywords: | KX-01, KX2-391 |
| Application: | Targets tyrosine-protein kinase Src [EC:2.7.10.2] (SRC) |
| CAS | 897016-82-9 |
| MW: | 431.53 D |
From 37.00€
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KX2-391
Item number: Cay21429-5
KX2-391 is an inhibitor of Src kinase (IC50 = ~20 nM). It is selective for Src over PDGFR, EGFR, JAK1, JAK2, Lck, and ZAP-70. KX2-391 induces cell cycle arrest at the G2/M phase and apoptosis in breast cancer cells expressing estrogen receptor alpha (ERalpha). It inhibits the growth of Huh7, PLC/PRF/5, Hep3B, and...
| Keywords: | KX 01, 5-[4-[2-(4-morpholinyl)ethoxy]phenyl]-N-(phenylmethyl)-2-pyridineacetamide |
| Application: | Src kinase inhibitor |
| CAS | 897016-82-9 |
| MW: | 431.5 D |
From 74.00€
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