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VX-11e
Item number: TGM-T3166-100mg
Description: VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor, antitumor agent. Target: FLT, Aurora Kinase, ERK, GSK-3, CDK. Smiles: Cc1cnc(Nc2ccc(F)cc2Cl)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1. References: Aronov AM, et al. J Med...
| Keywords: | TCS ERK 11e, Vertex-11e, VTX-11e |
| Application: | ERK2 inhibitor |
| CAS | 896720-20-0 |
| MW: | 500.35 D |
From 49.00€
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VX-11e
Item number: LKT-V9201.5
VX-11e inhibits ERK2 and exhibits anticancer activity. VX-11e also displays some inhibitory activity against aurora kinase A (AurA), glycogen synthase kinase 3 (GSK-3), CDK2, FLT3, ROCK1, and JNK3.
| Keywords: | ERK 11e, TCS ERK 11e |
| Application: | ERK2 inhibitor |
| CAS | 896720-20-0 |
| MW: | 500.35 D |
From 164.00€
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TCS ERK 11e
Item number: Cay19932-1
TCS ERK 11e is an orally bioavailable inhibitor of extracellular signal-related kinase 2 (ERK2, Ki i values of 395, 540, and 852 nM, respectively. TCS ERK 11e has been shown to block the proliferation of HT29 cells with an IC50 value of 48 nM.Formal Name:...
| Keywords: | TCS Extracellular Signal-Related Kinase 11e, VX-11e,... |
| Application: | ERK2 inhibitor |
| CAS | 896720-20-0 |
| MW: | 500.4 D |
From 52.00€
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