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Lipid-based Drug Delivery Tools from Cayman Chemical

Lipid-based drug delivery (LBDD) systems, such as LNPs, liposomes, and solid lipid nanoparticles (SLNs), are customizable platforms for the targeted delivery of pharmaceuticals and other therapeutic agents to cells and tissues. LBDD overcomes obstacles associated with conventional therapeutic formulations by encapsulating bioactive molecules in a lipid vesicle, which increases their bioavailability, distribution, and plasma half-life, and decreases systemic toxicity induced by off-target activity. The versatility of LBDD formulations is achievable in part through the diversity of lipids available for these applications. Our partner Cayman Chemical offers high-quality lipid components that can be used to build lipid particles as research tools, as well LNP Exploration Kits and Custom Lipid Synthesis to support preclinical research programs.

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Blog Article: Lipid-based Drug Delivery Development - Part 1
Blog Article: Lipid-based Drug Delivery Development - Part 2
Caymans Guide to Lipid Nanoparticle Formulation

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Lipid-based Drug Delivery Tools

1-Oleoyl-2-hydroxy-sn-glycero-3-PE

Item number: Cay25596-5

1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid...

Keywords:	18:1 LPE, 18:1 Lyso-PE, 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine,...
Application:	Lysophospholipid
CAS	89576-29-4
MW:	479.6 D

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