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BIBF 1202
Item number: TGM-TQ0321-100mg
Description: BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM). Target: VEGFR. Smiles: CN(C(=O)CN1CCN(C)CC1)c1ccc(N\C(=C2/C(=O)Nc3cc(ccc23)C(O)=O)c2ccccc2)cc1. References: Hilberg F, et al. BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumorefficacy. Cancer Res. 2008 Jun...
| Application: | Active metabolite, receptor tyrosine kinase inhibitor |
| CAS | 894783-71-2 |
| MW: | 525.6 D |
From 104.00€
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BIBF 1202
Item number: Cay27176-1
BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib, Cay-11022). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.Formal Name:...
| Keywords: | (3Z)-2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-car... |
| Application: | Active metabolite, Receptor tyrosine kinase inhibitor |
| CAS | 894783-71-2 |
| MW: | 525.6 D |
From 54.00€
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