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Item number: TGM-T15728-100mg

Description: LDN-212320 (OSU-0212320) is a glutamate transporter EAAT2 activator. It also enhances EAAT2 levels by > 6 fold at concentrations < 5 µM after 24 h. Target: transporter. Smiles: Cc1ccccc1CSc1ccc(nn1)-c1ccccn1. References: Xing X, et al. Structure-activity relationship study of pyridazine derivatives as...

Keywords:	LDN-0212320, OSU-0212320, LDN/OSU-0212320
Application:	EAAT2 expression activator
CAS	894002-50-7
MW:	293.39 D

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LDN-0212320

Item number: Cay21650-10

LDN-0212320 is an activator of excitatory amino acid transporter 2 (EAAT2) that increases expression of EAAT2 in PA-EAAT2 cells in a concentration- and time-dependent manner (EC50 = 1.83 µM). It selectively increases EAAT2 protein levels over EAAT1 and EAAT3 protein levels and increases glutamate uptake in primary...

Keywords:	OSU-0212320, 3-[[(2-methylphenyl)methyl]thio]-6-(2-pyridinyl)-pyridazine
Application:	EAAT2 expression activator
CAS	894002-50-7
MW:	293.4 D

From 85.00€ *

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