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Item number: Cay41829-1

Imirestat is an inhibitor of aldose reductase (IC50s = 24 and 18 nM for the rat and human enzymes, respectively). It reduces periodontal bone loss in a rat model of P. gingivalis LPS-induced periodontal inflammation and bone reabsorption when administered in the diet at 0.0125% (w/w). Dietary administration of...

Keywords:	AL 01576, Alcon 1576, HOE 843, 2,7-difluoro-spiro[9H-fluorene-9,4'-imidazolidine]-2',5'-dione
Application:	Aldose reductase inhibitor
CAS	89391-50-4
MW:	286.2 D

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Imirestat

Item number: TGM-T15568-100mg

Description: Imirestat (HOE 843) is an aldose reductase inhibitor that can be used in diabetes research. Target: Reductase. Smiles: Fc1ccc2-c3ccc(F)cc3C3(NC(=O)NC3=O)c2c1. References: Carrington AL, et al. Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of...

Keywords:	HOE 843, AL 1576, Alcon 1576
CAS	89391-50-4
MW:	286.23 D

From 74.00€ *

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