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Item number: TGM-T11647-10mg

Description: INCB 3284 dimesylate is a selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2 (IC50: 3.7 nM). It can be used in the research of acute liver failure. Target: Others. Smiles:...

CAS	887401-93-6
MW:	712.76 D

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INCB 3284 (dimesylate)

Item number: Cay11963-1

CCR2 is the receptor for the chemokine CCL2, known commonly as monocyte chemotactic protein-1 (MCP-1). INCB 3284 is a potent, selective, and orally bioavailable antagonist of monocyte chemotactic protein-1 binding to CCR2 (IC50 = 3.7 nM). For comparison, it has no significant inhibitor action at over 50 ion...

Keywords:	N-[2-[[(3R)-1-[trans-4-hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-...
Application:	MCP-1 binding antagonist
CAS	887401-93-6
MW:	712.8 D

From 48.00€ *

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