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AZD 2932
AZD 2932

Item number: Cay17741-1

AZD 2932 is an inhibitor of VEGFR2, PDGFRbeta, CSF1R, c-KIT, and FLT3 receptor tyrosine kinases (IC50s = 4, 8, 100, 9, and 7 nM, respectively). It also inhibits Pdgfralpha phosphorylation (IC50 = 2 nM) in lysates from C6 rat glial tumors grown in athymic mice. AZD 2932 (12.5-50 mg/kg) reduces tumor growth and...
Keywords: 4-[(6,7-dimethoxy-4-quinazolinyl)oxy]-N-[1-(1-methylethyl)-1H-pyrazol-4-yl]-benzeneacetamide
Application: VEFGR2 / PDGFR inhibitor
CAS 883986-34-3
MW: 447.5 D
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