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Item number: Cay39168-10

SBI-115 is an antagonist of G protein-coupled bile acid receptor 1 (GPBAR1), also known as TGR5. It inhibits taurolithocholic acid-induced increases in cAMP levels in, and proliferation of, cholangiocytes isolated from patients with autosomal dominant polycystic kidney disease when used at concentrations of 100 and...

Keywords:	5-chloro-2-(ethylsulfonyl)-4-pyrimidinecarboxylic acid 3-methylphenyl ester
Application:	GPBAR1 antagonist
CAS	882366-16-7
MW:	340.8 D

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