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SBI-115
SBI-115

Item number: TGM-T7428-100mg

Description: SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5. Target: GPCR19. Smiles: CCS(=O)(=O)c1ncc(Cl)c(n1)C(=O)Oc1cccc(C)c1. References: Masyuk TV, Masyuk AI, Lorenzo Pisarello M,et al.TGR5 contributes to hepatic cystogenesis in rodents...
Application: GPBAR1 antagonist
CAS 882366-16-7
MW: 340.78 D
From 48.00€ *
Review
SBI-115
SBI-115

Item number: Cay39168-10

SBI-115 is an antagonist of G protein-coupled bile acid receptor 1 (GPBAR1), also known as TGR5. It inhibits taurolithocholic acid-induced increases in cAMP levels in, and proliferation of, cholangiocytes isolated from patients with autosomal dominant polycystic kidney disease when used at concentrations of 100 and...
Keywords: 5-chloro-2-(ethylsulfonyl)-4-pyrimidinecarboxylic acid 3-methylphenyl ester
Application: GPBAR1 antagonist
CAS 882366-16-7
MW: 340.8 D
From 74.00€ *
Review