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Item number: TGM-T5994-100mg

Description: KPT-6566 is a novel selective covalent pin1 inhibitor, KPT-6566 shows an IC50 of 640 nM and a Ki of 625.2 nM for PIN1 PPIase domain,and has anti-cancer activity. Target: Others. Smiles: CC(C)(C)c1ccc(cc1)S(=O)(=O)\N=C1/C=C(SCC(O)=O)C(=O)c2ccccc12. References: Zhang J , Zhao F , Yu X , et al....

Application:	Covalent PIN1 inhibitor
CAS	881487-77-0
MW:	443.54 D

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KPT-6566

Item number: Cay37308-10

KPT-6566 is a covalent inhibitor of peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1, IC50 = 0.64 µM), an enzyme that catalyzes cis-trans or trans-cis conformational changes around serine-phosphate or threonine-phosphate bonds. It inhibits cell proliferation, decreases hyperphosphorylation of...

Keywords:	2-[[4-[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]imino]-1,4-dihydro-1-oxo-2-naphthalenyl]thio]-acetic acid
Application:	Covalent PIN1 inhibitor
CAS	881487-77-0
MW:	443.5 D

From 116.00€ *

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