3 products were found matching "881202-45-5"!
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JNJ-26854165
Item number: LKT-J5237.1
MDM2 inhibitor.
| Keywords: | Serdemetan |
| Application: | MDM2 inhibitor |
| CAS | 881202-45-5 |
| MW: | 328.42 D |
From 162.00€
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JNJ-26854165
Item number: Cay16259-1
The E3 ubiquitin ligase known as murine double minute 2 (MDM2, HDM2 in humans) binds to and then ubiquitinates several proteins, most notably the tumor suppressor p53. JNJ-26854165 is an antagonist of MDM2 that suppresses the growth of cancer cell lines expressing wild-type p53 (IC50 values range from 240-440 nM)....
| Keywords: | Serdemetan, N1-[2-(1H-indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine |
| Application: | MDM2 antagonist |
| CAS | 881202-45-5 |
| MW: | 328.4 D |
From 52.00€
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Serdemetan
Item number: TGM-T2243-100mg
Description: Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity. Target: p53, Apoptosis, Mdm2, E1/E2/E3 Enzyme. Smiles: C(Cc1c[nH]c2ccccc12)Nc1ccc(Nc2ccncc2)cc1. References: Kojima K, et al. Mol Cancer Ther. 2010, 9(9), 2545-2557.
| Keywords: | JNJ-26854165 |
| Application: | MDM2 antagonist |
| CAS | 881202-45-5 |
| MW: | 328.41 D |
From 40.00€
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