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Item number: TGM-T6875-100mg

Description: Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent liver...

Keywords:	RDEA594
Application:	Targets SLC22A12 (URAT1)
CAS	878672-00-5
MW:	404.28 D

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Lesinurad

Item number: Cay23688-5

Lesinurad is an inhibitor of urate anion transporter 1 (URAT1, IC50s = 3.5 and 81 µM for human and rat transporters, respectively), a transporter that prevents renal urate resorption. It decreases uptake of urate by MDCK cells transfected with human URAT1. Lesinurad (80 mg/kg) also decreases serum levels of uric...

Keywords:	2-[[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic acid
Application:	URAT1 inhibitor
CAS	878672-00-5
MW:	404.3 D

From 78.00€ *

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