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Item number: TGM-T7681-100mg

Description: AZD-5069 is an chemokine receptor 2 antagonist (CXCR2, IC50 = 0.79 nM). Target: CXCR. Smiles: C[C@@H](Oc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1)[C@@H](O)CO. References: Nicholls D J , Wiley K , Dainty I , et al. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2...

Application:	CXCR2 antagonist
CAS	878385-84-3
MW:	476.52 D

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AZD 5069

Item number: Cay28297-5

AZD 5069 is an antagonist of chemokine receptor 2 (CXCR2, IC50 = 0.79 nM in a radioligand binding assay). It inhibits CXCL1-induced CD11b expression in and chemotaxis of isolated human neutrophils (pA2s = 6.9 and 9.1, respectively). AZD 5069 (3 and 10 µmol/kg) inhibits bronchoalveolar lavage fluid (BALF) neutrophil...

Keywords:	N-[2-[[(2,3-difluorophenyl)methyl]thio]-6-[(1R,2S)-2,3-dihydroxy-1-methylpropoxy]-4-pyrimidinyl]-1-azetidinesulfonamide
Application:	CXCR2 antagonist
CAS	878385-84-3
MW:	476.5 D

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Review

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