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Item number: TGM-T1783-100mg

Description: LXR-623 (WAY 252623) is an orally bioavailable and highly specifical synthetic modulator of LXR. Target: Liver X Receptor. Smiles: Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F. References: Katz A, et al. J Clin Pharmacol. 2009, 49(6):643-9.

Keywords:	WAY 252623, LXR623
Application:	LXR agonist
CAS	875787-07-8
MW:	422.78 D

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LXR-623

Item number: Cay21117-1

LXR-623 is a liver X receptor (LXR) modulator that acts as a partial agonist at LXRalpha and a full agonist at LXRbeta (IC50s = 179 and 24 nM, respectively). It is orally bioavailable and readily passes the blood-brain barrier. LXR-623 is anti-atherogenic in animal models of atherosclerosis, showing synergistic...

Keywords:	WAY-252623, 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
Application:	LXR agonist
CAS	875787-07-8
MW:	422.8 D

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