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Quisinostat dihydrochloride
Quisinostat dihydrochloride

Item number: TGM-T6865-100mg

Description: Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11, greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to...
Keywords: Quisinostat 2HCl, Quisinostat (JNJ-26481585) 2HCl, JNJ26854165(Quisinostat) 2HCl, JNJ-26481585 2HCl
Application: HDAC inhibitor
CAS 875320-31-3
MW: 467.39 D
From 60.00€ *
Review
JNJ-26481585 (hydrochloride)
JNJ-26481585 (hydrochloride)

Item number: Cay14088-1

JNJ-26481585 is a histone deacetylase (HDAC) inhibitor. It inhibits class I (IC50s = 0.11, 0.33, 4.86, and 4.26 nM for HDAC1, -2, -3, and -8, respectively), class IIa (IC50s = 0.64, 3.69, 119, and 32.1 nM for HDAC4, -5, 7-, and -9, respectively), and class IIb HDACs (IC50s = 76.8 and 0.46 nM for HDAC6 and HDAC10,...
Keywords: Quisinostat, N-hydroxy-2-[4-[[[(1-methyl-1H-indol-3-yl)methyl]amino]methyl]-1-piperidinyl]-5-pyrimidinecarboxamide
Application: HDAC inhibitor
CAS 875320-31-3
MW: 467.4 D
From 111.00€ *
Review