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Quisinostat
Quisinostat

Item number: TGM-T6055-100mg

Description: Quisinostat (JNJ-26481585) (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11, greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Target: HDAC, Apoptosis,...
Keywords: JNJ-26481585
Application: Antineoplastic, Histone deacetylase inhibitor
CAS 875320-29-9
MW: 394.47 D
From 55.00€ *
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Quisinostat
Quisinostat

Item number: SYN-3029-M001

Quisinostat (JNJ-26481585) is a novel second-generation panHDAC inhibitor of HDAC1, 2, 4, 10 and 11. Its highest potency is against HDAC1 with an IC50 of 0.11nM. It has only modest potency against HDACs 2, 4, 10, and 11 (IC50 ranging from 0.33nM to 0.64nM). It has low activity against HDACs 3, 5, 8, and 9 and its...
Keywords: JNJ-26481585
Application: pan-HDAC inhibitor (HDAC1, 2, 4, 10, 11)
CAS 875320-29-9
MW: 394.5 D
From 139.00€ *
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Selonsertib Hydrochloride
Selonsertib Hydrochloride

Item number: SYN-1229-M100

Solid. Soluble in DMSO or ethanol. LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Keywords: LY-2784544
Application: JAK2 inhibitor
CAS 875320-29-9
MW: 469,9 D
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