3 products were found matching "872573-93-8"!
No results were found for the filter!
Ro 3306
Item number: Cay15149-1
Cyclin-dependent kinase 1 (Cdk1) complexes with different cyclins, with the cyclin determining substrate specificity. Ro 3306 is a cell-permeable, reversible inhibitor of Cdk1, showing preference for Cdk1/cyclin B1 (Ki = 35 nM) over Cdk1/cyclin A (Ki = 110 nM), two CDK complexes which regulate cell cycling. It also...
| Keywords: | 5Z-(6-quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone |
| Application: | CDK1 inhibitor |
| CAS | 872573-93-8 |
| MW: | 351.4 D |
From 52.00€
*
RO-3306
Item number: AG-CR1-3515-M005
Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M. Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at...
| Keywords: | (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one |
| Application: | CDK1 inhibitor, Apoptosis inducer |
| CAS | 872573-93-8 |
| MW: | 351,5 D |
From 33.00€
*
Ro-3306
Item number: TGM-T2356-100mg
Description: RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for CDK1 is >15-fold higher than a diverse panel of human kinases. Target: CDK, ERK, SGK, Apoptosis, PKC, PKA. Smiles: O=C1N=C(NCc2cccs2)SC1=Cc1ccc2ncccc2c1. References: Yang W, et al. Accumulation of...
| CAS | 872573-93-8 |
| MW: | 351.45 D |
From 33.00€
*
