4 products were found matching "872511-34-7"!
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Infigratinib
Item number: TGM-T1975-100mg
Description: Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2. Target: Apoptosis, FGFR. Smiles: CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)cc1. References: Guagnano V, et al....
| Keywords: | BGJ-398, NVP-BGJ398 |
| Application: | Targets fibroblast growth factor receptor 1 [EC:2.7.10.1] (FGFR1, CD331) |
| CAS | 872511-34-7 |
| MW: | 560.48 D |
From 41.00€
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BGJ398
Item number: Cay19157-1
BGJ398 is an orally available inhibitor of human FGFRs (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively). It inhibits FGFR4 and VEGFR2 with IC50 values of 60 and 180 nM, respectively, and displays comparatively little activity towards Abl, Fyn, Kit, Lck, Lyn, and Yes (IC50s = 0.3-2.5 µM). BGJ398...
| Keywords: | NVP-BGJ398, Infigratinib,... |
| Application: | FGFR1 / FGFR2 / FGFR3 inhibitor |
| CAS | 872511-34-7 |
| MW: | 560.5 D |
From 86.00€
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NVP-BGJ398
Item number: LKT-N8662.25
FGFR inhibitor.
| Keywords: | BGJ398, BGJ-398 |
| Application: | FGFR inhibitor |
| CAS | 872511-34-7 |
| MW: | 560.48 D |
From 124.00€
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NVP-BGJ398
Item number: SYN-1152-M001
Soluble in DMSO or ethanol. NVP-BGJ398 inhibits FGFR-WT, FGFR2-WT, FGFR3-K650E, FGFR3-S249C and FGFR4-WT with IC(50) values of 4.6, 4.9, 5, 5 and 168nM, respectively. Target: FGFR , Kinase Group: RTK , Substrate: Tyrosine
| Keywords: | NVPBGJ398 |
| Application: | FGFR inhibitor |
| CAS | 872511-34-7 |
| MW: | 560,5 D |
From 92.00€
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