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SC66
Item number: TGM-T3132-10mg
Description: SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 µg/ml, at 72 h). Target: Apoptosis, Akt. Smiles: O=C1\C(CCC\C1=C/c1ccncc1)=C\c1ccncc1. References: Cusimano A, et al. Oncotarget. 2015 Jan 30,6(3):1707-22.
| Application: | AKT inhibitor |
| CAS | 871361-88-5 |
| MW: | 276.33 D |
From 40.00€
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SC-66
Item number: Cay10876-10
Akt activation requires binding of its pleckstrin homology domain (PHD) to membrane-associated phosphatidylinositol-3,4,5-trisphosphate (PIP3) or phosphatidylinositol-3,4-bisphosphate (PIP2). Increased Akt activity, e.g., through a gain-of-function mutation in the PHD of Akt1, is pivotal to many types of cancer....
| Keywords: | 2E,6E-bis(4-pyridinylmethylene)-cyclohexanone |
| Application: | AKT inhibitor |
| CAS | 871361-88-5 |
| MW: | 276.3 D |
From 52.00€
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