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Item number: Cay29024-1

CYM 5478 is a sphingosine-1-phosphate receptor 2 (S1P2) agonist (EC50 = 0.78 µM in a reporter assay). It is selective for S1P2 over S1P1 and S1P3-5 in a TGFalpha-shedding assay (EC50s = 119, 1,690, 1,950, >10,000, and >10,000 nM, respectively). CYM 5478 (0.1-10 µM) reduces serum starvation-induced decreases in C6...

Keywords:	1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone
Application:	Sphingosine-1-phosphate receptor 2 (S1P2) agonist
CAS	870762-83-7
MW:	388.4 D

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