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Item number: TGM-T4997-100mg

Description: Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist. Target: AChR. Smiles: [Br-].OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCOCc3ccccc3)(CC1)CC2. References: Cazzola M, et al. Pharmacology and therapeutics of bronchodilators. Pharmacol Rev. 2012 Jul,64(3):450-504.

Keywords:	GSK573719A
Application:	Bronchodilator, Muscarinic acetylcholine receptor antagonist
CAS	869113-09-7
MW:	508.49 D

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Umeclidinium (bromide)

Item number: Cay20700-10

Umeclidinium is an antagonist of muscarinic acetylcholine receptors (Kis = 0.05-0.16 nM for M1-M5 human recombinant receptors). It inhibits acetylcholine-induced activation of recombinant M3 receptors in CHO cell membranes (IC50 = 50 = 10 µM) and bronchoconstriction in mice when administered intranasally (ED50 =...

Keywords:	GSK573719, 4-(hydroxydiphenylmethyl)-1-[2-(phenylmethoxy)ethyl]-1-azoniabicyclo[2.2.2]octane, monobromide
Application:	Muscarinic acetylcholine receptor antagonist
CAS	869113-09-7
MW:	508.5 D

From 166.00€ *

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