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Item number: TGM-T7355-100mg

Description: IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain. Target: Others, iGluR. Smiles: Oc1c(Cl)cc(Cl)cc1CNc1ccc2nn[nH]c2c1. References: Bach A , Pedersen S W , Dorr L A , et al. Biochemical investigations of the...

Application:	nNOS-PSD-95 protein-protein interaction inhibitor
CAS	866927-10-8
MW:	309.15 D

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IC87201

Item number: Cay32973-10

IC87201 is an inhibitor of the protein-protein interaction between neuronal nitric oxide synthase (nNOS) and post-synaptic density protein 95 (PSD-95). It inhibits the binding of PSD-95 to nNOS (IC50 = 31 µM). IC87201 inhibits NMDA-induced cGMP production, a marker of PSD-95-dependent NOS activation, in primary rat...

Keywords:	2-[(1H-benzotriazol-6-ylamino)methyl]-4,6-dichloro-phenol
Application:	nNOS-PSD-95 protein-protein interaction inhibitor
CAS	866927-10-8
MW:	309.2 D

From 133.00€ *

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