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Dorsomorphin
Item number: Cay11967-5
Dorsomorphin is a potent, reversible inhibitor of AMPK (Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCtheta, PKA, and JAK3. Dorsomorphin can also dose-dependently inhibit the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3),...
| Keywords: | BML-275, Compound C, 6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine |
| Application: | AMPK inhibitor, autophagy inducer |
| CAS | 866405-64-3 |
| MW: | 399.5 D |
From 78.00€
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Dorsomorphin
Item number: TGM-T1977-100mg
Description: Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor activity. Target: Autophagy, AMPK, TGF-beta/Smad. Smiles:...
| Keywords: | Compound C, BML-275 |
| Application: | AMPK inhibitor, autophagy inducer |
| CAS | 866405-64-3 |
| MW: | 399.49 D |
From 48.00€
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Dorsomorphin
Item number: LKT-D582703.10
Inhibitor of ALK2, ALK3, ALK6, and AMPK.
| Keywords: | BML-275, Compound C, 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine, AMPK inhibitor,... |
| Application: | AMPK inhibitor, Autophagy inducer |
| CAS | 866405-64-3 |
| MW: | 399.5 D |
From 109.00€
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