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Item number: Cay15632-5

SN-38 is an inhibitor of topoisomerase I and an active metabolite of the prodrug irinotecan (Cay-14180). It is formed from irinotecan by carboxylesterases. SN-38 (0.1, 1, and 10 µM) induces topoisomerase I-dependent DNA cleavage in a cell-free assay. It induces DNA single-strand breaks in HT-29 colorectal...

Keywords:	7-ethyl-10-hydroxy-20(S)-Camptothecin, 7-Ethyl-10-Hydroxycamptothecin, NK 012,...
Application:	Potent DNA topoisomerase I inhibitor
CAS	86639-52-3
MW:	392.4 D

From 66.00€ *

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7-Ethyl-10-hydroxycamptothecin

Item number: LKT-C0154.10

Camptothecin derivative, topoisomerase I inhibitor.

Keywords:	SN-38, 7-ethyl-10-hydroxy-CPT, 4,11-diethyl-4,9-dihydroxy-1H-Pyrano[3',4':6,7]- indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Application:	Topoisomerase I inhibitor
CAS	86639-52-3
MW:	392.4 D

From 208.00€ *

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