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Item number: TGM-T4217-100mg

Description: INF39 is a noncytotoxic and irreversible NLRP3 inhibitor. Target: NOD-like Receptor (NLR), NOD. Smiles: CCOC(=O)C(=C)Cc1ccccc1Cl. References: Cocco M, et al. J Med Chem. 2017, 60(9):3656-3671.

Application:	Irreversible NLRP3 inflammasome inhibitor
CAS	866028-26-4
MW:	224.68 D

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INF39

Item number: Cay28476-10

INF39 is an irreversible inhibitor of the NLRP3 inflammasome. INF39 (10 µM) inhibits activation of caspase-1 and the release of IL-1beta and lactate dehydrogenase (LDH) induced by ATP (Cay-14498) or nigericin (Cay-11437) in LPS-primed bone marrow-derived macrophages (BMDMs). It reduces ATP-induced pyroptosis in...

Keywords:	2-chloro-alpha-methylene-benzenepropanoic acid, ethyl ester
Application:	Irreversible NLRP3 inflammasome inhibitor
CAS	866028-26-4
MW:	224.7 D

From 158.00€ *

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