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L-745,870 (hydrochloride)
Item number: Cay37586-10
L-745,870 is a dopamine D4 receptor antagonist (Ki = 0.43 nM). It is selective for dopamine D4 receptors over dopamine D2 and D3 receptors (Kis = 960 and 2,300 nM, respectively). It is also selective for dopamine D4 receptors over alpha2A-, alpha2B-, and alpha2C-adrenergic receptors (IC50s = 0.00043, 0.16, 0.17, and...
| Keywords: | 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine, trihydrochloride |
| Application: | Dopamine D4 receptor antagonist |
| CAS | 866021-03-6 |
| MW: | 472.7 D |
From 88.00€
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L-745870 trihydrochloride
Item number: TGM-T22904-100mg
Description: L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist. Target: Sigma receptor, 5-HT Receptor, Adrenergic Receptor, Dopamine Receptor. Smiles: ClC1=CC=C(C=C1)N2CCN(CC2)CC3=CNC4=C3C=CC=N4.Cl.Cl.Cl. References: Bristow LJ, et al. Schizophrenia and L-745,870, a novel...
| Keywords: | L-745,870 trihydrochloride |
| CAS | 866021-03-6 |
| MW: | 436.21 D |
From 67.00€
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