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Tideglusib
Item number: TGM-T3067-100mg
Description: Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities. Target: GSK-3. Smiles: O=c1sn(-c2cccc3ccccc23)c(=O)n1Cc1ccccc1. References: Domínguez JM, et al. J Biol Chem, 2012, 287(2), 893-90
| Keywords: | NP-12, NP031112 |
| Application: | Neuroprotective, GSK3beta inhibitor |
| CAS | 865854-05-3 |
| MW: | 334.39 D |
From 40.00€
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Tideglusib
Item number: Cay16727-50
Tideglusib is a thiadiazolidinone that prevents inflammation and neurodegeneration when injected into rat hippocampus concurrently with kainic acid, a compound that causes excitotoxicity. Tideglusib-induced neuroprotection, in this model, is attenuated by the PPARgamma antagonist GW9662 (Cay-70785). Interestingly,...
| Keywords: | NP031112, 2-(1-naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione |
| Application: | Neuroprotective, GSK3beta inhibitor |
| CAS | 865854-05-3 |
| MW: | 334.4 D |
From 45.00€
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