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Revefenacin
Item number: TGM-T7392-100mg
Description: Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease. Target: AChR. Smiles: CN(CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)C(=O)c1ccc(CN2CCC(CC2)C(N)=O)cc1. References: Pulido-Rios MT, McNamara A, Obedencio...
| Keywords: | GSK1160724, TD-4208 |
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 864750-70-9 |
| MW: | 597.75 D |
From 35.00€
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TD-4208
Item number: Cay36549-10
TD-4208 is an antagonist of muscarinic acetylcholine receptors (mAChRs, Kis = 0.42, 0.3, 0.18, and 0.55 nM for M1, M2, M3, and M4 receptors, respectively, in membranes from CHO-K1 cells expressing the human receptors). It is selective for these receptors over M5 muscarinic receptors (Ki = 6.31 nM in membranes from...
| Keywords: | Revefenacin, N-[1,1'-biphenyl]-2-yl-carbamic acid,... |
| Application: | Muscarinic acetylcholine receptor antagonist |
| CAS | 864750-70-9 |
| MW: | 597.8 D |
From 48.00€
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