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ML-180
Item number: TGM-T12075-100mg
Description: ML-180 (SR1848) is a potent inverse agonist of the orphan nuclear receptor liver receptor homolog 1 (LRH-1, NR5A2) with an IC50 of 3.7 µM. Target: Others. Smiles: Clc1cccc(c1)N1CCN(CC1)c1cc(=O)n(C2CCCCC2)c(=O)[nH]1. References: Busby S, et al. Discovery of Inverse Agonists for the Liver Receptor...
| Keywords: | SR1848 |
| Application: | NR5A2 inverse agonist |
| CAS | 863588-32-3 |
| MW: | 388.89 D |
From 31.00€
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ML-180
Item number: Cay15181-10
ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 µM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death...
| Keywords: | CID-3238389, SR1848, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione |
| Application: | NR5A2 inverse agonist |
| CAS | 863588-32-3 |
| MW: | 388.9 D |
From 50.00€
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