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Item number: TGM-T28124-100mg

Description: N106 is an activator of the SUMO-activating enzyme, E1 ligase, and triggers intrinsic sumoylation of SERCA2a. N106 can be used in studies about heart failure. Target: E1/E2/E3 Enzyme. Smiles: COc1ccc(cc1)-c1nnc(Nc2nc3c(OC)cccc3s2)o1. References: Kho C, et al. Small-molecule activation of SERCA2a...

Keywords:	N 106, N-106
Application:	SERCA2A sumoylation activator
CAS	862974-25-2
MW:	354.38 D

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N106

Item number: Cay30952-1

N106 is an activator of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 2A (SERCA2A) SUMOylation. It activates SUMO-activating enzyme E1, which increases SUMOylation and the activity of SERCA2A in isolated adult rat cardiomyocytes when used at concentrations ranging from 0.1 to 1 µM. N106 increases contractility in...

Keywords:	4-methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-2-benzothiazolamine
Application:	SERCA2A sumoylation activator
CAS	862974-25-2
MW:	354.4 D

From 61.00€ *

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