2 products were found matching "861214-33-7"!
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5'-Fluoroindirubinoxime
Item number: TGM-T8317-100mg
Description: 5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM). Target: FLT. Smiles: O\N=C1\C(\Nc2ccccc\12)=C1/C(=O)Nc2ccc(F)cc12. References: Kim SA, et al. Antitumor activity of novel indirubin derivatives in rat tumor model. Clin Cancer Res. 2007 Jan 1,13(1):253-9.
| Keywords: | 5'-FIO |
| Application: | FLT3 kinase inhibitor |
| CAS | 861214-33-7 |
| MW: | 295.27 D |
From 42.00€
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PD 082106
Item number: Cay29719-1
PD 082106 is an inhibitor of FMS-related tyrosine kinase 3 (FLT3, IC50 = 0.015 µM, respectively) and a derivative of indirubin (Cay-14155). It is selective for FLT3 over Met, Ron, EGFR, and the insulin receptor (IC50s = >10 µM for all) but does inhibit DRAK2 (IC50 = 0.62 µM), as well as VEGFR2 and Aurora A (IC50s =...
| Keywords: | 5'-FIO, 5'-Fluoroindirubinoxime, 3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one |
| Application: | FLT3 kinase inhibitor |
| CAS | 861214-33-7 |
| MW: | 295.3 D |
From 43.00€
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