Description: DNP-PEG4-NHS ester, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: O=C(ON1C(=O)CCC1=O)CCOCCOCCOC COCCNC2=CC=C(C=C2N(=O)=O)N(=O)=O....

CAS: 858126-78-0. Molecular weight: 528.47. Compared to the commonly used DNP-X SE (#2021), DNP-PEG4 NHS ester has much better water solubility. It is an excellent amine-reactive building block for developing DNP probes that can be recognized by anti-DNP antibodies. It might be also used as an excellent...