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Item number: Cay16848-10

AT7867 is a potent and orally bioavailable inhibitor of Akt isoforms Akt1, 2, and 3 (IC50s = 32, 17, and 47 nM, respectively). It also inhibits p70S6 kinase and PKA (IC50s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases. AT7867 inhibits growth and induces apoptosis in a variety...

Keywords:	4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]-piperidine
Application:	Akt Inhibitor
CAS	857531-00-1
MW:	337.9 D

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