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(-)-Blebbistatin
Item number: Cay13013-5
(-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases and the active enantiomer of (+)-blebbistatin (Cay-13165). It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 µM), while poorly...
| Keywords: | (S)-Blebbistatin, 1,2,3,3a-tetrahydro-3aS-hydroxy-6-methyl-1-phenyl-4H-Pyrrolo[2,3-b]quinolin-4-one |
| Application: | Non-muscle myosin II ATPase inhibitor |
| CAS | 856925-71-8 |
| MW: | 292.3 D |
From 78.00€
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(-)-Blebbistatin
Item number: TGM-T6038-100mg
Description: (-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 µM. Target: ATPase, Myosin. Smiles: Cc1ccc2N=C3N(CC[C@@]3(O)C(=O)c2c1)c1ccccc1. References: Liu Z, et al. Blebbistatin inhibits contraction and...
| Keywords: | (S)-(-)-Blebbistatin |
| Application: | Non-muscle myosin II ATPase inhibitor |
| CAS | 856925-71-8 |
| MW: | 292.33 D |
From 37.00€
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(-)-Blebbistatin
Item number: ABD-80001
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of 2 uM. It does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.
| Application: | Non-muscle myosin II ATPase inhibitor |
| CAS | 856925-71-8 |
| MW: | 292,33 D |
141.00€
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