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Item number: TGM-TQ0313-100mg

Description: NVP-BAG956 is an ATP-competitive PI3K inhibitor with IC50 values of 34 nM for PI3Kdelta, 56 nM for PI3Kalpha, 112 nM for PI3Kgamma, and 444 nM for PI3Kbeta. Target: PI3K. Smiles: Cc1nc2cnc3ccc(cc3c2n1-c1ccc(cc1)C(C)(C)C#N)C#Cc1cccnc1. References: Marone R, et al. Targeting melanoma with dual...

Keywords:	BAG956
Application:	PDK1 inhibitor, PI3K inhibitor
CAS	853910-02-8
MW:	427.5 D

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NVP-BAG956

Item number: Cay24195-1

NVP-BAG956 is a dual inhibitor of 3-phosphoinositide-dependent protein kinase 1 (PDK1, IC50 = 245 nM) and class I phosphatidylinositol 3-kinase catalytic subunits (PI3Ks, IC50s = 56, 446, 35, and 117 nM for p110alpha, p110beta, p110delta, and p110gamma, respectively). It inhibits phosphorylation of T308-PKB (IC50 =...

Keywords:	BAG956, alpha,alpha-dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile
Application:	PDK1 inhibitor, PI3K inhibitor
CAS	853910-02-8
MW:	427.5 D

From 52.00€ *

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