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PF-00489791
PF-00489791

Item number: TGM-T28360-10mg

Description: PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy. Target: PDE. Smiles: C(NS(C)(=O)=O)(=O)C=1C=2C(=C(NC3=CC(C)=CC=N3)N=C(N(CC)C)N2)N(CCOCC)N1. References: Scheele W, Diamond S, Gale J, Clerin V, Tamimi N, Le V, Walley R, Grover-Páez...
Keywords: PF4634817, PF 00489791, PF-4634817, PF 4634817, PF00489791
Application: PDE5A inhibitor
CAS 853003-48-2
MW: 476.55 D
From 103.00€ *
Review
PF-00489791
PF-00489791

Item number: Cay40464-1

PF-00489791 is an inhibitor of phosphodiesterase 5A (PDE5A, IC50 = 1.9 nM). It does not cross the blood-brain barrier in rats. PF-00489791 (10 mg/kg) improves motor scores in a rat model of stroke induced by middle cerebral artery occlusion (MCAO).Formal Name:...
Keywords: PF-489791, UK 489791,...
Application: PDE5A inhibitor
CAS 853003-48-2
MW: 476.6 D
From 39.00€ *
Review