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MC1568
Item number: TGM-T2023-100mg
Description: MC1568 is a specific HDAC inhibitor for maize HD1-A (IC50: 100 nM, in a cell-free assay). It is 34-fold more selective for HD1-A than HD1-B. Target: HDAC. Smiles: Cn1c(\C=C\C(=O)NO)ccc1\C=C\C(=O)c1cccc(F)c1. References: Mai A, et al. J Med Chem, 2005, 48(9), 3344-3353.
| CAS | 852475-26-4 |
| MW: | 314.31 D |
From 33.00€
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MC 1568
Item number: Cay16265-1
While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which includes HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. MC 1568 is a selective inhibitor of...
| Keywords: | (2E)-3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide |
| Application: | Selective class IIa HDAC inhibitor |
| CAS | 852475-26-4 |
| MW: | 314.3 D |
From 44.00€
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MC1568
Item number: LKT-M0803.25
HDAC inhibitor. May reduce blood pressure in hypertensive animals.
| Keywords: | (2E)-3-{4-[(1E)-3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxyacrylamide |
| Application: | HDAC inhibitor. May reduce blood pressure in hypertensive animals |
| CAS | 852475-26-4 |
| MW: | 314.32 D |
From 204.00€
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