2 products were found matching "852391-15-2"!
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Necrostatin 2 racemate
Item number: TGM-T7504-100mg
Description: Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1. Target: RIP kinase. Smiles: CN1C(=O)NC(Cc2c[nH]c3c(Cl)cccc23)C1=O. References: Takahashi N , Duprez L , Grootjans S , et al. Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use...
| Keywords: | Necrostatin-2 racemate |
| Application: | Cell-permeable RIP1 inhibitor |
| CAS | 852391-15-2 |
| MW: | 277.71 D |
From 58.00€
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(±)-Necrostatin-2
Item number: Cay20924-1
(±)-Necrostatin-2 is a racemic mixture that inhibits receptor-interacting protein kinase 1 (RIPK1) autophosphorylation in vitro in a dose-dependent manner. Treatment with 6 mg/kg/day of (±)-necrostatin-2 prevents TNF-induced mortality in a murine model of systemic inflammatory response syndrome (SIRS)....
| Keywords: | 7-Cl-O-Nec-1, Nec-1s, 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione |
| Application: | Cell-permeable RIP1 inhibitor |
| CAS | 852391-15-2 |
| MW: | 277.7 D |
From 54.00€
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