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Item number: TGM-T77745-100mg

Description: N6F11 is a novel, selective and potent inducer of ferroptosis with anticancer and antitumour activity that promotes GPX4 degradation by binding to TRIM25 in cancer cells.N6F11 can be used to study pancreatic cancer. Target: GPX. Smiles: ClCC1=NC2=C(SC(=C2)C2=CC=C(Cl)C=C2)C(=O)N1. References: Li J, et...

Application:	Ferroptosis inducer, GPX4 degradation inducer
CAS	851398-76-0
MW:	311.19 D

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N6F11

Item number: Cay39919-25

N6F11 is an inducer of ferroptosis. It increases the thermal stability of the ubiquitin ligase TRIM25 in a cellular thermal shift assay (CETSA) using PANC-1 pancreatic cancer cells when used at a concentration of 10 µM and enhances TRIM25-dependent ubiquitination of glutathione peroxidase 4 (GPX4) in a cell-free...

Keywords:	2-(chloromethyl)-6-(4-chlorophenyl)-thieno[3,2-d]pyrimidin-4(3H)-one
Application:	Ferroptosis inducer, GPX4 degradation inducer
CAS	851398-76-0
MW:	313.2 D

From 47.00€ *

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