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Item number: TGM-T8426-100mg

Description: Encequidar (HM30181A) is a potent and selective P-glycoprotein inhibitor. Target: P-gp. Smiles: COc1cc2CCN(CCc3ccc(cc3)-n3nnc(n3)-c3cc(OC)c(OC)cc3NC(=O)c3cc(=O)c4ccccc4o3)Cc2cc1OC. References: Bauer F, et al. Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with...

Keywords:	HM30181, HM30181A
Application:	Targets ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2] (ABCB1, CD243)
CAS	849675-66-7
MW:	688.73 D

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HM30181

Item number: Cay32873-1

HM30181 is an inhibitor of P-glycoprotein (P-gp), also known as multidrug resistance protein 1 (MDR1, IC50 = 0.63 nM). It is selective for P-gp over breast cancer resistance protein (BCRP, IC50 = 3,700 nM), as well as multidrug resistance-associated protein 1 (MRP1), MRP2, and MRP3 at 100 µM. It inhibits...

Keywords:	Encequidar,...
Application:	P-glycoprotein inhibitor
CAS	849675-66-7
MW:	688.7 D

From 50.00€ *

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