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Bentamapimod
Item number: TGM-T2675-100mg
Description: Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK. Target: JNK. Smiles: N#C\C(=C1\Nc2ccccc2S1)c1ccnc(OCc2ccc(CN3CCOCC3)cc2)n1. References: Messoussi A, et al. Recent progress in the design, study, and development of c-Jun N-terminal kinase inhibitors as anticanceragents. Chem Biol....
| Keywords: | AS 602801 |
| Application: | JNK1 / JNK2 / JNK3 inhibitor |
| CAS | 848344-36-5 |
| MW: | 457.55 D |
From 40.00€
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Bentamapimod
Item number: Cay21482-1
Bentamapimod is an orally bioavailable inhibitor of Jun kinases (JNKs), with IC50 values for JNK1, JNK2, and JNK3 of 80, 90, and 230 nM, respectively. It is selective for JNKs over a panel of 25 related kinases. Bentamapimod induces regression of endometriotic lesions without suppressing estrogen action in animal...
| Keywords: | AS-602801, alpha-[2-[[4-(4-morpholinylmethyl)phenyl]methoxy]-4-pyrimidinyl]-2-benzothiazoleacetonitrile |
| Application: | JNK1 / JNK2 / JNK3 inhibitor |
| CAS | 848344-36-5 |
| MW: | 457.5 D |
From 55.00€
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Bentamapimod
Item number: SYN-1147-M001
Soluble in DMSO. Bentamapimod (AS602801) is a novel and orally active c-Jun-N-Terminal Kinase Inhibitor highly specific for JNK kinases. The inhibitor Bentamapimod (AS602801) is a potent anti-inflammatory agent which has been shown to reduce the disease burden in several pre-clinical models for endometriosis, and...
| Keywords: | AS-602801 |
| Application: | JNK inhibitor |
| CAS | 848344-36-5 |
| MW: | 457,6 D |
From 293.00€
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