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Alvelestat
Alvelestat

Item number: TGM-T3107-100mg

Description: Alvelestat (AZD9668) is an orally bioavailable, selective, and reversible inhibitor of human neutrophil elastase (NE), exhibiting potential anti-inflammatory activity. Target: Others, Serine Protease. Smiles: Cc1c(cc(C(=O)NCc2ccc(cn2)S(C)(=O)=O)c(=O)n1-c1cccc(c1)C(F)(F)F)-c1ccnn1C. References: Stevens...
Keywords: AZD9668, Avelestat
Application: Neutrophil elastase inhibitor
CAS 848141-11-7
MW: 545.53 D
From 31.00€ *
Review
AZD 9668
AZD 9668

Item number: Cay26083-1

AZD 9668 is an orally bioavailable inhibitor of neutrophil elastase (IC50 = 12 nM for the human enzyme). It is greater than 600-fold selective for neutrophil elastase over other serine proteases, including human proteinase-3 and cathepsin G, bovine trypsin and chymotrypsin, and porcine pancreatic elastase. AZD 9668...
Keywords: 1,2-dihydro-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-N-[[5-(methylsulfonyl)-2-pyridinyl]methyl]-2-oxo-1-[3-(trifluoromethyl)p...
Application: Neutrophil elastase inhibitor
CAS 848141-11-7
MW: 545.5 D
From 61.00€ *
Review