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VER-82576
Item number: TGM-T2114-100mg
Description: VER-82576 (NVP-BEP800), a synthetic HSP90beta inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94. Target: HSP. Smiles: CCNC(=O)c1cc2c(nc(N)nc2s1)-c1cc(OCCN2CCCC2)c(Cl)cc1Cl. References: Massey AJ, et al. Mol Cancer Ther, 2010, 9(4), 906-919.
| Keywords: | NVP-BEP800 |
| Application: | Hsp90 beta inhibitor |
| CAS | 847559-80-2 |
| MW: | 480.41 D |
From 40.00€
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NVP-BEP800
Item number: Cay18383-1
NVP-BEP800 is an inhibitor of heat shock protein 90 (Hsp90, IC50 = 58 nM for recombinant human Hsp90beta). It is selective for Hsp90 over the chaperones GRP94 and TRAP1 (IC50s = 4.1 and 5.5 µM, respectively). NVP-BEP800 inhibits the growth of BT474, SK-BR-3, MCF-7, MDA-MB-157, MDA-MB-231, MDA-MB-468, and BT-20...
| Keywords: | 2-amino-4-[2,4-dichloro-5-[2-(1-pyrrolidinyl)ethoxy]phenyl]-N-ethyl-thieno[2,3-d]pyrimidine-6-carboxamide |
| Application: | Hsp90 beta inhibitor |
| CAS | 847559-80-2 |
| MW: | 480.4 D |
From 61.00€
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